Endocrine Abstracts

Introduction: GH producing pituitary adenomas are associated with infertility. Hereby the first case in Lithuania, when acromegaly patient got pregnant and delivered is reported.Case presentation: 33-year-old woman visited endocrinologist complaining of secondary amenorrhoea. Due to elevated prolactin – 3016 mU/l (NR<418), bromcriptine treatment was started. The patient discontinued treatment after three months because of restoration of regular ...

Introduction: Even though the importance of nutrition in diabetes development is well known, little has been done to explore whether nutrition affects reproductive health and escalates the risk for further consequences of deterioration of metabolic parameters in young men.The goal of our study was to evaluate a possible relationship between eating patterns, metabolic parameters and androgenisation levels in healthy young men.Method...

Introduction: Parathyroid carcinoma (PC) is an extremely rare, aggressive and life-threatening form of primary hyperparathyroidism (pHPT). PC accounts for less than 1% of cases of pHPT, predominantly diagnosed in the fifth or sixth decades of life. Most parathyroid carcinomas are diagnosed after surgery.Case description: A 51-year old man was admitted to the Hospital of Lithuanian University of Health Sciences, Kaunas clinics due to leg pain and general ...

Introduction: Hypothyroidism is associated with a spectrum of symptoms affecting almost all bodily functions. We present a case of severe hypothyroidism with multiple body cavity effusions, volvulus of sigma creating ileus.Case report: A 70 year old female was admitted to emergency department with dyspnea, and acute abdominal pain. Physical examination was notable for anasarca, abdominal fluid wave, lower extremity pitting edema, hypotension. She did not...

Introduction: Tumor-induced osteomalacia (TIO) or oncogenic hypophosphatemic osteomalacia (OHO) is a rare paraneoplastic syndrome characterized by renal phosphate wasting leading to hypophosphatemia and secondary osteomalacia. TIO was first described in 1947 by Robert McCance and only 500 of cases have been reported in literature since then, approximately 200 of cases during this decade.Case report: In 2014, a 32-year-old female presented with waist pain...

Introduction: Two major strategies can be used to verify the diagnosis of ascending aortic dilatation in Turner syndrome (TS): the diameter of the aorta adjusted for body surface area (BSA) can be estimated or the ratio of the ascending/descending aorta may be assessed.Aim: To identify the difference of the prevalence of ascending aortic dilatation in patients with Turner syndrome by measuring the diameter of the ascending aorta adjusted for BSA and by e...

Introduction: Turner syndrome (TS) is associated with specific physical features, as well as a particular neuropsychological profile and social and behavioral features. It is common practice in the case of TS to treat short stature with growth hormone preparations and to induce puberty with estrogens at an age as close to normal puberty as possible. Nevertheless results of some studies show that despite the treatment, some women with TS still experience psychosocial problems, ...

Introduction: Stereotactic radiotherapy and more relevant pharmacotherapy are widely used for PA’s treatment; however transsphenoidal surgery remains gold standard. Postoperative complications and endocrinological outcomes vary widely and are related with surgeon experience and tumor characteristics.The aim of this study: To determine relationship between pituitary adenoma size and transsphenoidal pituitary adenoma surgery outcomes.<p class="abs...

Resistance to thyroid hormone beta (RTH?) is a rare disorder which poses challenges in both diagnostics and management. The prevalence varies from 1/19,000 to 1/40,000. In 14% of individuals manifesting with RTH? phenotype no THRB mutations were identified. The management of these patients, especially after total thyroidectomy, in the absence of generalized consensus is complicated. 36-year-old woman was referred to endocrinologist with symptoms of thyrotoxicosis and dissonant...

Introduction: Papillary thyroid carcinoma (PTC) is the most common type of differentiated thyroid cancer of all cases of thyroid cancer. Fine-needle biopsy by ultrasonography is still the main diagnostic method of PTC, but there is a technical limitation. That’s why, a minimally invasive diagnostic test that can accurately diagnose the onset of the disease is the subject of research.Our objective: We aimed to explore the concentration levels of ...